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In-vivo PK in Small and Large animals
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In-vivo rodent pharmacokinetics Bioavailability/Repeated/ Single / Multiple dose in rats, mice, rabbits, zebra fish

Bioavailability: Obtaining data from pharmacokinetic studies in rats, mice and rabbits is the most crucial steps of drug discovery. Determination of the drug exposure of the compound is

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In-vivo ADMET First pass / EHC / Portal / Excretion

In-vivo pharmacokinetic studies are done in rats, mice, rabbits and others like zebrafish systems. First Pass: Clinically, first-pass metabolism is important when the fraction of the dose administered

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Surgical Skills / Route of Administration / Species / Matrices

For these studies, surgical expertise is important i.e. animals are cannulated either by jugular or portal or bile or femoral to infuse or administer compound as well as

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Tissue Distribution studies in Rodents, zebra fish

In-vivo tissue distribution in rats, mice, rabbits, and other aquatic system like zebra fish provides an in depth analysis of the metabolic fate of the compound within various






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